Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress

We previously reported that p53-mediated apoptosis is determined by severity of DNA damage, not by the level of p53, in doxorubicin-treated prostate cancer cells. In addition to doxorubicin, our results here indicated that camptothecin and bortezomib, which are a topoisomerase 1 poison and a 26 S pr...

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Detalles Bibliográficos
Autores principales: Ho, Cheng-Jung, Lin, Ru-Wei, Zhu, Wei-Hua, Wen, Tsung-Kai, Hu, Chieh-Ju, Lee, Yi-Lin, Hung, Ta-I, Wang, Chihuei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711993/
https://www.ncbi.nlm.nih.gov/pubmed/31482012
http://dx.doi.org/10.1038/s41420-019-0211-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711993/
https://www.ncbi.nlm.nih.gov/pubmed/31482012
http://dx.doi.org/10.1038/s41420-019-0211-5

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