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Transcription-independent and -dependent p53-mediated apoptosis in response to genotoxic and non-genotoxic stress
We previously reported that p53-mediated apoptosis is determined by severity of DNA damage, not by the level of p53, in doxorubicin-treated prostate cancer cells. In addition to doxorubicin, our results here indicated that camptothecin and bortezomib, which are a topoisomerase 1 poison and a 26 S pr...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711993/ https://www.ncbi.nlm.nih.gov/pubmed/31482012 http://dx.doi.org/10.1038/s41420-019-0211-5 |