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Vimentin regulates Notch signaling strength and arterial remodeling in response to hemodynamic stress

The intermediate filament (IF) cytoskeleton has been proposed to regulate morphogenic processes by integrating the cell fate signaling machinery with mechanical cues. Signaling between endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) through the Notch pathway regulates arterial remod...

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Detalles Bibliográficos
Autores principales: van Engeland, Nicole C. A., Suarez Rodriguez, Freddy, Rivero-Müller, Adolfo, Ristori, Tommaso, Duran, Camille L., Stassen, Oscar M. J. A., Antfolk, Daniel, Driessen, Rob C. H., Ruohonen, Saku, Ruohonen, Suvi T., Nuutinen, Salla, Savontaus, Eriika, Loerakker, Sandra, Bayless, Kayla J., Sjöqvist, Marika, Bouten, Carlijn V. C., Eriksson, John E., Sahlgren, Cecilia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712036/
https://www.ncbi.nlm.nih.gov/pubmed/31455807
http://dx.doi.org/10.1038/s41598-019-48218-w