Cyclin A2 degradation during the spindle assembly checkpoint requires multiple binding modes to the APC/C

The anaphase-promoting complex/cyclosome (APC/C) orchestrates cell cycle progression by controlling the temporal degradation of specific cell cycle regulators. Although cyclin A2 and cyclin B1 are both targeted for degradation by the APC/C, during the spindle assembly checkpoint (SAC), the mitotic c...

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Detalles Bibliográficos
Autores principales: Zhang, Suyang, Tischer, Thomas, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712056/
https://www.ncbi.nlm.nih.gov/pubmed/31455778
http://dx.doi.org/10.1038/s41467-019-11833-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712056/
https://www.ncbi.nlm.nih.gov/pubmed/31455778
http://dx.doi.org/10.1038/s41467-019-11833-2

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