Identification of an ERK Inhibitor as a Therapeutic Drug Against Tau Aggregation in a New Cell-Based Assay

Formation of Tau aggregates is a common pathological feature of tauopathies and their accumulation directly correlates with cytotoxicity and neuronal degeneration. Great efforts have been made to understand Tau aggregation and to find therapeutics halting or reversing the process, however, progress...

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Detalles Bibliográficos
Autores principales: Siano, Giacomo, Caiazza, Maria Claudia, Ollà, Ivana, Varisco, Martina, Madaro, Giuseppe, Quercioli, Valentina, Calvello, Mariantonietta, Cattaneo, Antonino, Di Primio, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712076/
https://www.ncbi.nlm.nih.gov/pubmed/31496937
http://dx.doi.org/10.3389/fncel.2019.00386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712076/
https://www.ncbi.nlm.nih.gov/pubmed/31496937
http://dx.doi.org/10.3389/fncel.2019.00386

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