Synthesis and antitumor evaluation of neolaxiflorin B inspired compounds

BACKGROUND: Neolaxiflorin B is derived from ent-kaurane like laxiflorin J and eriocalyxin B with a relatively low potency as an antitumor agent. During preliminary structure–activity relationship studies, the α,β-unsaturated ketone (enone) system is an important active group. METHODS: Seven neolaxif...

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Detalles Bibliográficos
Autores principales: Liu, Jing-Ping, Xiao, Ye-Zhi, Hu, Yu, Li, Xiao-Nian, Wu, Ming-Jiang, Zhao, Yong, Zhao, Yan, Ma, Ze-Jin, Shen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712212/
https://www.ncbi.nlm.nih.gov/pubmed/31692523
http://dx.doi.org/10.2147/DDDT.S202345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712212/
https://www.ncbi.nlm.nih.gov/pubmed/31692523
http://dx.doi.org/10.2147/DDDT.S202345

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