Cargando…
Synthesis and antitumor evaluation of neolaxiflorin B inspired compounds
BACKGROUND: Neolaxiflorin B is derived from ent-kaurane like laxiflorin J and eriocalyxin B with a relatively low potency as an antitumor agent. During preliminary structure–activity relationship studies, the α,β-unsaturated ketone (enone) system is an important active group. METHODS: Seven neolaxif...
Autores principales: | Liu, Jing-Ping, Xiao, Ye-Zhi, Hu, Yu, Li, Xiao-Nian, Wu, Ming-Jiang, Zhao, Yong, Zhao, Yan, Ma, Ze-Jin, Shen, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712212/ https://www.ncbi.nlm.nih.gov/pubmed/31692523 http://dx.doi.org/10.2147/DDDT.S202345 |
Ejemplares similares
-
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells
por: Hu, Yu, et al.
Publicado: (2018) -
Design and Synthesis of Pro-Apoptotic Compounds Inspired by Diatom Oxylipins
por: Romano, Giovanna, et al.
Publicado: (2013) -
Trienamine catalyzed asymmetric synthesis and biological investigation of a cytochalasin B-inspired compound collection
por: Sellstedt, Magnus, et al.
Publicado: (2016) -
Sporopollenin-inspired design and synthesis of robust polymeric materials
por: Glinkerman, Christopher M., et al.
Publicado: (2022) -
Design, synthesis, and antihypertensive activity of curcumin-inspired compounds via ACE inhibition and vasodilation, along with a bioavailability study for possible benefit in cardiovascular diseases
por: Zhuang, Xiao-dong, et al.
Publicado: (2016)