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Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication

Using multiple viral systems, and performing silencing approaches, overexpression approaches, and experiments in knockout cells, we report, for the first time, that interferon (IFN)-induced protein 44 (IFI44) positively affects virus production and negatively modulates innate immune responses induce...

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Detalles Bibliográficos
Autores principales: DeDiego, Marta L., Nogales, Aitor, Martinez-Sobrido, Luis, Topham, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712396/
https://www.ncbi.nlm.nih.gov/pubmed/31455651
http://dx.doi.org/10.1128/mBio.01839-19