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Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication
Using multiple viral systems, and performing silencing approaches, overexpression approaches, and experiments in knockout cells, we report, for the first time, that interferon (IFN)-induced protein 44 (IFI44) positively affects virus production and negatively modulates innate immune responses induce...
Autores principales: | DeDiego, Marta L., Nogales, Aitor, Martinez-Sobrido, Luis, Topham, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712396/ https://www.ncbi.nlm.nih.gov/pubmed/31455651 http://dx.doi.org/10.1128/mBio.01839-19 |
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