Distinct Binding Interactions of α(5)β(1)-Integrin and Proteoglycans with Fibronectin

Dynamic single-molecule force spectroscopy was performed to monitor the unbinding of fibronectin with the proteoglycans syndecan-4 (SDC4) and decorin and to compare this with the unbinding characteristics of α(5)β(1)-integrin. A single energy barrier was sufficient to describe the unbinding of both...

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Detalles Bibliográficos
Autores principales: Kennelly, Thomas M., Li, Yiran, Cao, Yi, Qwarnstrom, Eva E., Geoghegan, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712418/
https://www.ncbi.nlm.nih.gov/pubmed/31337547
http://dx.doi.org/10.1016/j.bpj.2019.07.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712418/
https://www.ncbi.nlm.nih.gov/pubmed/31337547
http://dx.doi.org/10.1016/j.bpj.2019.07.002

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