Oxygen Uptake Rate Soft-Sensing via Dynamic k(L)a Computation: Cell Volume and Metabolic Transition Prediction in Mammalian Bioprocesses

In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to be in right balance with the consumption by cells....

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Detalles Bibliográficos
Autores principales: Pappenreiter, Magdalena, Sissolak, Bernhard, Sommeregger, Wolfgang, Striedner, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712683/
https://www.ncbi.nlm.nih.gov/pubmed/31497597
http://dx.doi.org/10.3389/fbioe.2019.00195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712683/
https://www.ncbi.nlm.nih.gov/pubmed/31497597
http://dx.doi.org/10.3389/fbioe.2019.00195

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