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Oxygen Uptake Rate Soft-Sensing via Dynamic k(L)a Computation: Cell Volume and Metabolic Transition Prediction in Mammalian Bioprocesses
In aerobic cell cultivation processes, dissolved oxygen is a key process parameter, and an optimal oxygen supply has to be ensured for proper process performance. To achieve optimal growth and/or product formation, the rate of oxygen transfer has to be in right balance with the consumption by cells....
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712683/ https://www.ncbi.nlm.nih.gov/pubmed/31497597 http://dx.doi.org/10.3389/fbioe.2019.00195 |