Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice

BACKGROUND: HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are generally well tolerated, but adverse reactions may occur, particularly myopathy and new onset of diabetes. The exact mechanism...

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Detalles Bibliográficos
Autores principales: Lorza-Gil, Estela, García-Arevalo, Marta, Favero, Bianca Cristine, Gomes-Marcondes, Maria Cristina C., Oliveira, Helena C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712816/
https://www.ncbi.nlm.nih.gov/pubmed/31455371
http://dx.doi.org/10.1186/s12967-019-2045-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712816/
https://www.ncbi.nlm.nih.gov/pubmed/31455371
http://dx.doi.org/10.1186/s12967-019-2045-6

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