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Diabetogenic effect of pravastatin is associated with insulin resistance and myotoxicity in hypercholesterolemic mice
BACKGROUND: HMG-CoA reductase inhibitors (statins) are cholesterol-lowering drugs widely used to treat hypercholesterolemia and prevent cardiovascular disease. Statins are generally well tolerated, but adverse reactions may occur, particularly myopathy and new onset of diabetes. The exact mechanism...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712816/ https://www.ncbi.nlm.nih.gov/pubmed/31455371 http://dx.doi.org/10.1186/s12967-019-2045-6 |