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SUMOylation regulates USP5-Cav3.2 calcium channel interactions

Cav3.2 calcium channels play a key role in nociceptive signaling in the primary afferent pain pathway. We have previously reported the regulation of Cav3.2 calcium channels by the deubiquitinase USP5 and its importance for regulating peripheral transmission of pain signals. Here we describe the regu...

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Detalles Bibliográficos
Autores principales: Garcia-Caballero, Agustin, Zhang, Fang-Xiong, Chen, Lina, M’Dahoma, Said, Huang, Junting, Zamponi, Gerald W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712834/
https://www.ncbi.nlm.nih.gov/pubmed/31455361
http://dx.doi.org/10.1186/s13041-019-0493-9