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Metabolomics combined with network pharmacology exploration reveals the modulatory properties of Astragali Radix extract in the treatment of liver fibrosis

BACKGROUND: Astragali Radix (AR) is widely-used for improving liver fibrosis, but, the mechanism of action has not been systematically explained. This study aims to investigate the mechanism of AR intervention in liver fibrosis based on comprehensive metabolomics combined with network pharmacology a...

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Detalles Bibliográficos
Autores principales: Wang, Dan, Li, Ruisheng, Wei, Shizhang, Gao, Sijia, Xu, Zhuo, Liu, Honghong, Wang, Ruilin, Li, Haotian, Cai, Huadan, Wang, Jian, Zhao, Yanling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712842/
https://www.ncbi.nlm.nih.gov/pubmed/31467589
http://dx.doi.org/10.1186/s13020-019-0251-z