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(1)H-NMR metabolomics reveals the Glabrescione B exacerbation of glycolytic metabolism beside the cell growth inhibitory effect in glioma

BACKGROUND: Glioma is the most common and primary brain tumors in adults. Despite the available multimodal therapies, glioma patients appear to have a poor prognosis. The Hedgehog (Hh) signaling is involved in tumorigenesis and emerged as a promising target for brain tumors. Glabrescione B (GlaB) ha...

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Detalles Bibliográficos
Autores principales: D’Alessandro, Giuseppina, Quaglio, Deborah, Monaco, Lucia, Lauro, Clotilde, Ghirga, Francesca, Ingallina, Cinzia, De Martino, Michela, Fucile, Sergio, Porzia, Alessandra, Di Castro, Maria Amalia, Bellato, Federica, Mastrotto, Francesca, Mori, Mattia, Infante, Paola, Turano, Paola, Salmaso, Stefano, Caliceti, Paolo, Di Marcotullio, Lucia, Botta, Bruno, Ghini, Veronica, Limatola, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712882/
https://www.ncbi.nlm.nih.gov/pubmed/31455353
http://dx.doi.org/10.1186/s12964-019-0421-8