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Improved homology modeling of the human & rat EP(4) prostanoid receptors

BACKGROUND: The EP(4) prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E(2) (PGE(2)). Novel selective EP(4) receptor agonists would assist to further elucidate receptor sub-type function and promote development of therapeutics for bone healing, heart failure...

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Detalles Bibliográficos
Autores principales: Holt, Melissa C., Ho, Chi S., Morano, M. Inés, Barrett, Stephen D., Stein, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712885/
https://www.ncbi.nlm.nih.gov/pubmed/31455205
http://dx.doi.org/10.1186/s12860-019-0212-5