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Improved homology modeling of the human & rat EP(4) prostanoid receptors
BACKGROUND: The EP(4) prostanoid receptor is one of four GPCRs that mediate the diverse actions of prostaglandin E(2) (PGE(2)). Novel selective EP(4) receptor agonists would assist to further elucidate receptor sub-type function and promote development of therapeutics for bone healing, heart failure...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712885/ https://www.ncbi.nlm.nih.gov/pubmed/31455205 http://dx.doi.org/10.1186/s12860-019-0212-5 |