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Conventional and Chemically Programmed Asymmetric Bispecific Antibodies Targeting Folate Receptor 1

T-cell engaging bispecific antibodies (biAbs) can mediate potent and specific tumor cell eradication in liquid cancers. Substantial effort has been invested in expanding this concept to solid cancers. To explore their utility in the treatment of ovarian cancer, we built a set of asymmetric biAbs in...

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Detalles Bibliográficos
Autores principales: Qi, Junpeng, Hymel, David, Nelson, Christopher G., Burke, Terrence R., Rader, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712926/
https://www.ncbi.nlm.nih.gov/pubmed/31497024
http://dx.doi.org/10.3389/fimmu.2019.01994