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Analysis of cell-free circulating tumor DNA in 419 patients with glioblastoma and other primary brain tumors

AIM: Genomically matched trials in primary brain tumors (PBTs) require recent tumor sequencing. We evaluated whether circulating tumor DNA (ctDNA) could facilitate genomic interrogation in these patients. METHODS: Data from 419 PBT patients tested clinically with a ctDNA NGS panel at a CLIA-certifie...

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Detalles Bibliográficos
Autores principales: Piccioni, David E, Achrol, Achal Singh, Kiedrowski, Lesli A, Banks, Kimberly C, Boucher, Najee, Barkhoudarian, Garni, Kelly, Daniel F, Juarez, Tiffany, Lanman, Richard B, Raymond, Victoria M, Nguyen, Minhdan, Truong, Judy D, Heng, Annie, Gill, Jaya, Saria, Marlon, Pingle, Sandeep C, Kesari, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713031/
https://www.ncbi.nlm.nih.gov/pubmed/30855176
http://dx.doi.org/10.2217/cns-2018-0015