Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity

A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA) ratio and lactate dehydrogenase (LDH) activi...

Descripción completa

Detalles Bibliográficos
Autores principales: Guglielmi, Paolo, Secci, Daniela, Petzer, Anél, Bagetta, Donatella, Chimenti, Paola, Rotondi, Giulia, Ferrante, Claudio, Recinella, Lucia, Leone, Sheila, Alcaro, Stefano, Zengin, Gokhan, Petzer, Jacobus P., Ortuso, Francesco, Carradori, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713090/
https://www.ncbi.nlm.nih.gov/pubmed/31422706
http://dx.doi.org/10.1080/14756366.2019.1653864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713090/
https://www.ncbi.nlm.nih.gov/pubmed/31422706
http://dx.doi.org/10.1080/14756366.2019.1653864

Ejemplares similares