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Benzo[b]tiophen-3-ol derivatives as effective inhibitors of human monoamine oxidase: design, synthesis, and biological activity

A series of benzo[b]thiophen-3-ols were synthesised and investigated as potential human monoamine oxidase (hMAO) inhibitors in vitro as well as ex vivo in rat cortex synaptosomes by means of evaluation of 3,4-dihydroxyphenylacetic acid/dopamine (DOPAC/DA) ratio and lactate dehydrogenase (LDH) activi...

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Detalles Bibliográficos
Autores principales:	Guglielmi, Paolo, Secci, Daniela, Petzer, Anél, Bagetta, Donatella, Chimenti, Paola, Rotondi, Giulia, Ferrante, Claudio, Recinella, Lucia, Leone, Sheila, Alcaro, Stefano, Zengin, Gokhan, Petzer, Jacobus P., Ortuso, Francesco, Carradori, Simone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713090/ https://www.ncbi.nlm.nih.gov/pubmed/31422706 http://dx.doi.org/10.1080/14756366.2019.1653864

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