Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors

Novel sulfonamide-dithiocarbamate hybrids were designed and synthesised via the molecular hybridisation strategy. Among them, compound 13d displayed a potent activity with IC(50) values of 0.9, 0.7, 1.9 and 2.6 µM against UM-UC-3, RT-112, RT4 and T24. Compound 13d inhibited the migration and regulat...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Liu, Chunlai, Zhang, Xiling, Yu, Liu, Gong, Xue, Wang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713100/
https://www.ncbi.nlm.nih.gov/pubmed/31401884
http://dx.doi.org/10.1080/14756366.2019.1639696

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713100/
https://www.ncbi.nlm.nih.gov/pubmed/31401884
http://dx.doi.org/10.1080/14756366.2019.1639696

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