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Dehydration affects drug transport over nasal mucosa

Formulations for nasal drug delivery often rely on water sorption to adhere to the mucosa, which also causes a higher water gradient over the tissue and subsequent dehydration. The primary aim of this study was therefore to evaluate mucosal response to dehydration and resolve the hypothesis that muc...

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Detalles Bibliográficos
Autores principales: Ali, Abdullah, Wahlgren, Marie, Rembratt-Svensson, Birgitta, Daftani, Ameena, Falkman, Peter, Wollmer, Per, Engblom, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713119/
https://www.ncbi.nlm.nih.gov/pubmed/31401887
http://dx.doi.org/10.1080/10717544.2019.1650848