Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach

Carbonic anhydrases (CAs) are ubiquitous metallo-enzymes that catalyse the reversible hydration of carbon dioxide to bicarbonate and proton. In humans there are 15 isoforms among which only 12 are catalytically active. Since active human (h) CAs show different efficiency, the understanding of the mo...

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Detalles Bibliográficos
Autores principales: De Simone, Giuseppina, Di Fiore, Anna, Truppo, Emanuela, Langella, Emma, Vullo, Daniela, Supuran, Claudiu T., Monti, Simona Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713127/
https://www.ncbi.nlm.nih.gov/pubmed/31431090
http://dx.doi.org/10.1080/14756366.2019.1653290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713127/
https://www.ncbi.nlm.nih.gov/pubmed/31431090
http://dx.doi.org/10.1080/14756366.2019.1653290

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