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Glycan modification of glioblastoma-derived extracellular vesicles enhances receptor-mediated targeting of dendritic cells

Glioblastoma is the most prevalent and aggressive primary brain tumour for which total tumour lysate-pulsed dendritic cell vaccination is currently under clinical evaluation. Glioblastoma extracellular vesicles (EVs) may represent an enriched cell-free source of tumour-associated (neo-) antigens to...

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Detalles Bibliográficos
Autores principales: Dusoswa, Sophie A., Horrevorts, Sophie K., Ambrosini, Martino, Kalay, Hakan, Paauw, Nanne J., Nieuwland, Rienk, Pegtel, Michiel D., Würdinger, Tom, Van Kooyk, Yvette, Garcia-Vallejo, Juan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713149/
https://www.ncbi.nlm.nih.gov/pubmed/31489145
http://dx.doi.org/10.1080/20013078.2019.1648995