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Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity

In this investigation, we studied a family of compounds with an oxathiazolidine-4-one-2,2-dioxide skeleton and their amide synthetic precursors as new anticonvulsant drugs. The cyclic structures were synthesized using a three-step protocol that include solvent-free reactions and microwave-assisted h...

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Detalles Bibliográficos
Autores principales: Sabatier, Laureano L., Palestro, Pablo H., Enrique, Andrea V., Pastore, Valentina, Sbaraglini, María L., Martín, Pedro, Gavernet, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713207/
https://www.ncbi.nlm.nih.gov/pubmed/31411081
http://dx.doi.org/10.1080/14756366.2019.1651722