Role of the voltage sensor module in Na(v) domain IV on fast inactivation in sodium channelopathies: The implication of closed-state inactivation

The segment 4 (S4) voltage sensor in voltage-gated sodium channels (Na(v)s) have domain-specific functions, and the S4 segment in domain DIV (DIVS4) plays a key role in the activation and fast inactivation processes through the coupling of arginine residues in DIVS4 with residues of putative gating...

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Detalles Bibliográficos
Autores principales: Nakajima, Tadashi, Kaneko, Yoshiaki, Dharmawan, Tommy, Kurabayashi, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713248/
https://www.ncbi.nlm.nih.gov/pubmed/31357904
http://dx.doi.org/10.1080/19336950.2019.1649521

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713248/
https://www.ncbi.nlm.nih.gov/pubmed/31357904
http://dx.doi.org/10.1080/19336950.2019.1649521

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