Delineating the role of FANCA in glucose-stimulated insulin secretion in β cells through its protein interactome

Hyperinsulinemia affects 72% of Fanconi anemia (FA) patients and an additional 25% experience lowered glucose tolerance or frank diabetes. The underlying molecular mechanisms contributing to the dysfunction of FA pancreas β cells is unknown. Therefore, we sought to evaluate the functional role of FA...

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Detalles Bibliográficos
Autores principales: Lagundžin, Dragana, Hu, Wen-Feng, Law, Henry C. H., Krieger, Kimiko L., Qiao, Fangfang, Clement, Emalie J., Drincic, Andjela T., Nedić, Olgica, Naldrett, Michael J., Alvarez, Sophie, Woods, Nicholas T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713327/
https://www.ncbi.nlm.nih.gov/pubmed/31461451
http://dx.doi.org/10.1371/journal.pone.0220568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713327/
https://www.ncbi.nlm.nih.gov/pubmed/31461451
http://dx.doi.org/10.1371/journal.pone.0220568

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