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A bigenic mouse model of FSGS reveals perturbed pathways in podocytes, mesangial cells and endothelial cells

Focal segmental glomerulosclerosis is a major cause of end stage renal disease. Many patients prove unresponsive to available therapies. An improved understanding of the molecular basis of the disease process could provide insights leading to novel therapeutic approaches. In this study we carried ou...

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Detalles Bibliográficos
Autores principales: Potter, Andrew S., Drake, Keri, Brunskill, Eric W., Potter, S. Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713350/
https://www.ncbi.nlm.nih.gov/pubmed/31461442
http://dx.doi.org/10.1371/journal.pone.0216261