When drug treatments bias genetic studies: Mediation and interaction

BACKGROUND: Increasingly, genetic analyses are conducted using information from subjects with established disease, who often receive concomitant treatment. We determined when treatment may bias genetic associations with a quantitative trait. METHODS: Graph theory and simulated data were used to expl...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Amand F., Heerspink, Hiddo J. L., Denig, Petra, Finan, Chris, Groenwold, Rolf H. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713387/
https://www.ncbi.nlm.nih.gov/pubmed/31461463
http://dx.doi.org/10.1371/journal.pone.0221209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713387/
https://www.ncbi.nlm.nih.gov/pubmed/31461463
http://dx.doi.org/10.1371/journal.pone.0221209

Ejemplares similares