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When drug treatments bias genetic studies: Mediation and interaction
BACKGROUND: Increasingly, genetic analyses are conducted using information from subjects with established disease, who often receive concomitant treatment. We determined when treatment may bias genetic associations with a quantitative trait. METHODS: Graph theory and simulated data were used to expl...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713387/ https://www.ncbi.nlm.nih.gov/pubmed/31461463 http://dx.doi.org/10.1371/journal.pone.0221209 |