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Bacterial lipopolysaccharide and antimicrobial LL-37 enhance ICAM-1 expression and NF-κB p65 phosphorylation in senescent endothelial cells

Cellular senescence is associated with the induction of a proinflammatory phenotype. Notably, senescent endothelial cells are detected at the sites of atherosclerotic lesions, suggesting the involvement of senescent endothelial cells in atherogenesis. Moreover, bacterial infection has been speculate...

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Detalles Bibliográficos
Autores principales: Suzuki, Kaori, Ohkuma, Mari, Nagaoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713406/
https://www.ncbi.nlm.nih.gov/pubmed/31364735
http://dx.doi.org/10.3892/ijmm.2019.4294