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Simvastatin promotes endothelial dysfunction by activating the Wnt/β-catenin pathway under oxidative stress

Atherosclerosis is a major pathogenic factor in patients with cardiovascular diseases, and endothelial dysfunction (ED) plays a primary role in its occurrence and development. Simvastatin is a lipid-lowering drug, which is commonly used to prevent or treat risk factors of cardiovascular diseases wit...

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Detalles Bibliográficos
Autores principales: He, Zhiqiang, Du, Xinyue, Wu, Yifan, Hua, Lingyue, Wan, Linxi, Yan, Nianlong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713427/
https://www.ncbi.nlm.nih.gov/pubmed/31432100
http://dx.doi.org/10.3892/ijmm.2019.4310