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Viperin catalyzes methionine oxidation to promote protein expression and function of helicases

Helicases play pivotal roles in fundamental biological processes, and posttranslational modifications regulate the localization, function, and stability of helicases. Here, we report that methionine oxidation of representative helicases, including DNA and RNA helicases of viral (ORF44 of KSHV) and c...

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Detalles Bibliográficos
Autores principales: Bai, Lei, Dong, Jiazhen, Liu, Zhenqiu, Rao, Youliang, Feng, Pinghui, Lan, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713503/
https://www.ncbi.nlm.nih.gov/pubmed/31489375
http://dx.doi.org/10.1126/sciadv.aax1031