A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, lethal malignancy that invades adjacent vasculatures and spreads to distant sites before clinical detection. Although invasion into the peripancreatic vasculature is one of the hallmarks of PDAC, paradoxically, PDAC tumors also exhibit hypova...

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Detalles Bibliográficos
Autores principales: Nguyen, Duc-Huy T., Lee, Esak, Alimperti, Styliani, Norgard, Robert J., Wong, Alec, Lee, Jake June-Koo, Eyckmans, Jeroen, Stanger, Ben Z., Chen, Christopher S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713506/
https://www.ncbi.nlm.nih.gov/pubmed/31489365
http://dx.doi.org/10.1126/sciadv.aav6789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713506/
https://www.ncbi.nlm.nih.gov/pubmed/31489365
http://dx.doi.org/10.1126/sciadv.aav6789

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