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A biomimetic pancreatic cancer on-chip reveals endothelial ablation via ALK7 signaling
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive, lethal malignancy that invades adjacent vasculatures and spreads to distant sites before clinical detection. Although invasion into the peripancreatic vasculature is one of the hallmarks of PDAC, paradoxically, PDAC tumors also exhibit hypova...
Autores principales: | Nguyen, Duc-Huy T., Lee, Esak, Alimperti, Styliani, Norgard, Robert J., Wong, Alec, Lee, Jake June-Koo, Eyckmans, Jeroen, Stanger, Ben Z., Chen, Christopher S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713506/ https://www.ncbi.nlm.nih.gov/pubmed/31489365 http://dx.doi.org/10.1126/sciadv.aav6789 |
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