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Inhibition of mitochondrial permeability transition by deletion of the ANT family and CypD

The mitochondrial permeability transition pore (MPTP) has resisted molecular identification. The original model of the MPTP that proposed the adenine nucleotide translocator (ANT) as the inner membrane pore-forming component was challenged when mitochondria from Ant1/2 double null mouse liver still...

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Detalles Bibliográficos
Autores principales: Karch, Jason, Bround, Michael J., Khalil, Hadi, Sargent, Michelle A., Latchman, Nadina, Terada, Naohiro, Peixoto, Pablo M., Molkentin, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713508/
https://www.ncbi.nlm.nih.gov/pubmed/31489369
http://dx.doi.org/10.1126/sciadv.aaw4597