Stress resilience is promoted by a Zfp189-driven transcriptional network in prefrontal cortex

Understanding transcriptional changes engaged in stress resilience may reveal novel antidepressant targets. Here, we use gene co-expression analysis of RNA-sequencing data from brains of resilient mice to identify a gene network that is unique to resilience. Zfp189, which encodes a previously unstud...

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Detalles Bibliográficos
Autores principales: Lorsch, Zachary S., Hamilton, Peter J., Ramakrishnan, Aarthi, Parise, Eric M., Salery, Marine, Wright, William J., Lepack, Ashley E., Mews, Philipp, Issler, Orna, McKenzie, Andrew, Zhou, Xianxiao, Parise, Lyonna F., Pirpinias, Stephen T., Torres, Idelisse Ortiz, Kronman, Hope G., Montgomery, Sarah E., Loh, Yong-Hwee Eddie, Labonté, Benoit, Conkey, Andrew, Symonds, Ann E., Neve, Rachael L., Turecki, Gustavo, Maze, Ian, Dong, Yan, Zhang, Bin, Shen, Li, Bagot, Rosemary C., Nestler, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713580/
https://www.ncbi.nlm.nih.gov/pubmed/31427770
http://dx.doi.org/10.1038/s41593-019-0462-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713580/
https://www.ncbi.nlm.nih.gov/pubmed/31427770
http://dx.doi.org/10.1038/s41593-019-0462-8

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