Effects of palbociclib on oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

OBJECTIVE: Lack of effective therapies remains a problem in the treatment of oral squamous cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is driven by multiple aberrancies within the cell cycle pathway, including amplification of cyclin D1 and loss of p16. Hence...

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Detalles Bibliográficos
Autores principales: Zainal, Nur Syafinaz, Lee, Bernard Kok Bang, Wong, Zheng Wei, Chin, Iuan Sheau, Yee, Pei San, Gan, Chai Phei, Mun, Kein Seong, Rahman, Zainal Ariff Abdul, Gutkind, J. Silvio, Patel, Vyomesh, Cheong, Sok Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713638/
https://www.ncbi.nlm.nih.gov/pubmed/31516747
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713638/
https://www.ncbi.nlm.nih.gov/pubmed/31516747
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0257

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