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Attenuated plasmodium sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice
OBJECTIVE: Cancer vaccines that rely on tumor antigen-specific CD8(+) T cell responses, are promising anti-cancer adjuvant immunotherapies. This study investigated whether genetically attenuated Plasmodium sporozoite (GAS) could be used as a novel vector to induce antigen-specific CD8(+) T cell resp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Anti-Cancer Association
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713645/ https://www.ncbi.nlm.nih.gov/pubmed/31516749 http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0309 |