Attenuated plasmodium sporozoite expressing MAGE-A3 induces antigen-specific CD8+ T cell response against lung cancer in mice

OBJECTIVE: Cancer vaccines that rely on tumor antigen-specific CD8(+) T cell responses, are promising anti-cancer adjuvant immunotherapies. This study investigated whether genetically attenuated Plasmodium sporozoite (GAS) could be used as a novel vector to induce antigen-specific CD8(+) T cell resp...

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Detalles Bibliográficos
Autores principales: Zhou, Dong, Zheng, Hong, Liu, Quanxing, Lu, Xiao, Deng, Xufeng, Jiang, Li, Hou, Bing, Fu, Yong, Zhu, Feng, Ding, Yan, Xu, Wenyue, Dai, Jigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Anti-Cancer Association 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713645/
https://www.ncbi.nlm.nih.gov/pubmed/31516749
http://dx.doi.org/10.20892/j.issn.2095-3941.2018.0309

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