Development of Tigecycline Resistance in Carbapenemase-Producing Klebsiella pneumoniae Sequence Type 147 via AcrAB Overproduction Mediated by Replacement of the ramA Promoter

BACKGROUND: Carbapenem-resistant K. pneumoniae 2297, isolated from a patient treated with tigecycline for pneumonia, developed tigecycline resistance, in contrast to carbapenem-resistant isolate 1215, which was collected four months prior to the 2297 isolate. Mechanisms underlying tigecycline resist...

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Detalles Bibliográficos
Autores principales: Yoon, Eun-Jeong, Oh, Yena, Jeong, Seok Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713659/
https://www.ncbi.nlm.nih.gov/pubmed/31432634
http://dx.doi.org/10.3343/alm.2020.40.1.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713659/
https://www.ncbi.nlm.nih.gov/pubmed/31432634
http://dx.doi.org/10.3343/alm.2020.40.1.15

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