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Modulation of autoimmune pathogenesis by T cell-triggered inflammatory cell death

T cell-mediated autoimmunity encompasses diverse immunopathological outcomes; however, the mechanisms underlying this diversity are largely unknown. Dysfunction of the tripartite linear ubiquitin chain assembly complex (LUBAC) is associated with distinct autonomous immune-related diseases. Cpdm mice...

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Detalles Bibliográficos
Autores principales: Sasaki, Katsuhiro, Himeno, Ai, Nakagawa, Tomoko, Sasaki, Yoshiteru, Kiyonari, Hiroshi, Iwai, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713751/
https://www.ncbi.nlm.nih.gov/pubmed/31462647
http://dx.doi.org/10.1038/s41467-019-11858-7