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Endogenous RNAi pathway evolutionarily shapes the destiny of the antisense lncRNAs transcriptome

Antisense long noncoding (aslnc)RNAs are extensively degraded by the nuclear exosome and the cytoplasmic exoribonuclease Xrn1 in the budding yeast Saccharomyces cerevisiae, lacking RNAi. Whether the ribonuclease III Dicer affects aslncRNAs in close RNAi-capable relatives remains unknown. Using genom...

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Detalles Bibliográficos
Autores principales: Szachnowski, Ugo, Andjus, Sara, Foretek, Dominika, Morillon, Antonin, Wery, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713810/
https://www.ncbi.nlm.nih.gov/pubmed/31462400
http://dx.doi.org/10.26508/lsa.201900407