Effect of Ambrisentan Therapy on the Expression of Endothelin Receptor, Endothelial Nitric Oxide Synthase and NADPH Oxidase 4 in Monocrotaline-induced Pulmonary Arterial Hypertension Rat Model

BACKGROUND AND OBJECTIVES: Elevated endothelin (ET)-1 level is strongly correlated with the pathogenesis of pulmonary arterial hypertension (PAH). Expression level of nicotinamide adenine dinucleotide phosphate oxidase (NOX) 4 is increased in the PAH patients. Ambrisentan, a selective endothelin rec...

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Detalles Bibliográficos
Autores principales: Lee, Hyeryon, Yeom, Arim, Kim, Kwan Chang, Hong, Young Mi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Cardiology 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713827/
https://www.ncbi.nlm.nih.gov/pubmed/31165592
http://dx.doi.org/10.4070/kcj.2019.0006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713827/
https://www.ncbi.nlm.nih.gov/pubmed/31165592
http://dx.doi.org/10.4070/kcj.2019.0006

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