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Thymine DNA glycosylase recognizes the geometry alteration of minor grooves induced by 5-formylcytosine and 5-carboxylcytosine

The dynamic DNA methylation–demethylation process plays critical roles in gene expression control and cell development. The oxidation derivatives of 5-methylcytosine (5mC) generated by Tet dioxygenases in the demethylation pathway, namely 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5...

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Detalles Bibliográficos
Autores principales: Fu, Tianran, Liu, Liping, Yang, Qing-Lin, Wang, Yuxin, Xu, Pan, Zhang, Lin, Liu, Shien, Dai, Qing, Ji, Quanjiang, Xu, Guo-Liang, He, Chuan, Luo, Cheng, Zhang, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713860/
https://www.ncbi.nlm.nih.gov/pubmed/31489163
http://dx.doi.org/10.1039/c9sc02807b