Successful Brain Delivery of Andrographolide Loaded in Human Albumin Nanoparticles to TgCRND8 Mice, an Alzheimer’s Disease Mouse Model

Andrographolide (AG) was encapsulated in human albumin nanoparticles (AG NPs), and their crossing properties of the blood-brain barrier (BBB), brain distribution, and effects in TgCRND8 mice were evaluated. The development of appropriate NP formulations is mandatory because of the scarce BBB permeab...

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Detalles Bibliográficos
Autores principales: Bilia, Anna Rita, Nardiello, Pamela, Piazzini, Vieri, Leri, Manuela, Bergonzi, Maria Camilla, Bucciantini, Monica, Casamenti, Fiorella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713928/
https://www.ncbi.nlm.nih.gov/pubmed/31507412
http://dx.doi.org/10.3389/fphar.2019.00910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713928/
https://www.ncbi.nlm.nih.gov/pubmed/31507412
http://dx.doi.org/10.3389/fphar.2019.00910

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