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Roles of Factor XII in Innate Immunity

Factor XII (FXII) is the zymogen of serine protease, factor XIIa (FXIIa). FXIIa enzymatic activities have been extensively studied and FXIIa inhibition is emerging as a promising target to treat or prevent thrombosis without creating a hemostatic defect. FXII and plasma prekallikrein reciprocally ac...

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Detalles Bibliográficos
Autores principales: Renné, Thomas, Stavrou, Evi X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713930/
https://www.ncbi.nlm.nih.gov/pubmed/31507606
http://dx.doi.org/10.3389/fimmu.2019.02011