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A fast, miniaturised in-vitro assay developed for quantification of lipase enzyme activity

The discovery of allosteric modulators is a multi-disciplinary approach, which is time- and cost-intensive. High-throughput screening combined with novel computational tools can reduce these factors. Thus, we developed an enzyme activity assay, which can be included in the drug discovery work-flow s...

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Detalles Bibliográficos
Autores principales: Menden, Ariane, Hall, Davane, Paris, Daniel, Mathura, Venkatarian, Crawford, Fiona, Mullan, Michael, Crynen, Stefan, Ait-Ghezala, Ghania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6713963/
https://www.ncbi.nlm.nih.gov/pubmed/31414611
http://dx.doi.org/10.1080/14756366.2019.1651312